A Case of Gastrinoma in a Shih-Tzu Dog

Journal of Veterinary Medical Science

Hiroshi ITO²  Shozo OKANO⁴  Masami UECHI¹  Ushio FUKUSHIMA¹  Toshifumi OYAMADA³  Kazuki YOSHIOKA⁵  Miyuki SATO¹  Yoshitaka ARAMAKI² 

[1] Veterinary Teaching Hospital, School of Veterinary Medicine and Animal Sciences, Kitasato University;Department of Veterinary Surgery, School of Veterinary Medicine and Animal Sciences, Kitasato University;Department of Veterinary Pathology, School of Veterinary Medicine and Animal Sciences, Kitasato University;Department of Small Animal Medicine, School of Veterinary Medicine and Animal Sciences, Kitasato University;Department of Veterinary Anatomy, School of Veterinary Medicine and Animal Sciences, Kitasato University

关键词: canine;    gastrinoma;    Zollinger-Ellison syndrome;   

DOI  :  10.1292/jvms.66.311

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(16)Cited-By(3)A five-year-old male Shih-Tzu dog presented with severe vomiting and weight loss. The clinical signs were successfully improved by an eight-day treatment with an H2-receptor antagonist, gastrointestinal protectant and antibiotics. Ten days later, however, recurrence of vomiting was seen despite continuous medical treatment. Based on clinical signs and the results of various diagnostic tests including CBC, biochemical analysis, contrast radiography, and endoscopy, a duodenal or pancreatic neoplasm was suspected and exploratory laparotomy was conducted. Some swollen pancreatic regions were found, and biopsy of the pancreas indicated the diagnosis of a gastrin-secreting tumor. Consequently, based on a high serum gastrin level as well as clinical signs and immunohistological findings, we diagnosed the disease as canine gastrinoma, a rare tumor of the pancreas.

【 授权许可】

Unknown