How far have we come in terms of estrogens in breast cancer? [Review]

Endocrine Journal

Fouzia Guestini¹  Kyoko Kikuchi¹  Hironobu Sasano¹  Keely May McNamara¹  Minako Sakurai¹ 

[1] Department of Anatomic Pathology, Tohoku University Graduate School of Medicine, Sendai 980-8575, Japan

关键词: Breast cancer;    Sex steroid;    Hormones;    Hormone receptors;   

DOI  :  10.1507/endocrj.EJ16-0022

学科分类：内分泌与代谢学

来源: Japan Endocrine Society

【 摘 要 】

References(78)Major advances in breast cancer treatment have almost always been linked to the actions of estrogen.Therefore, this review focused on estrogen actions in the breast, particularly the developments of the past 20 years, the present understanding of disease biology and possible future developments.Within these areas have focused on what is known about the underlying molecular biology and in particular integration of the bioinformatics revolution of the last 15 years with other facets of research.In addition, there will be an emphasis on the understanding brought about by a greater appreciation for the intracrinology of the breast.

【 授权许可】

Unknown