Web-based BEST-KIT: Webをベースにした生物化学工�? システム解析用ツールキットの開発

Chem-Bio Informatics Journal

櫻庭 健司¹  岡本 正宏³  上野 純一¹  下之�? 匡弘¹  関口 達也²  �? 正和¹  吉村 淳¹  田中 康司¹ 

[1] 九州工業大学情報工学部生物化学システム工学科;前橋工科大学工学部情報工学科;九州大学大学院農学研究院生物機能科学部門生物機能制御学講座

关键词: Web-based simulator;    ウェッブベースシミュレータ;    computer simulation;    コンピュータシミュレーション;    optimization;    �?適化;    metabolic pathway;    代謝経路;    bioinformatics;    バイオインフォマティクス;   

DOI  :  10.1273/cbij.2.1

学科分类：生物化学/生物物理

来源: Chem-Bio Informatics Society

【 摘 要 】

References(14)Cited-By(2)We have implemented an efficient, user-friendly, and web-based "biosimulator" named called BEST-KIT (Biochemical Engineering System analyzing Tool-KIT: http://helios.brs.Kyushu -u.ac.jp/˜bestkit/) for analyzing a a large scalelarge scale nonlinear reaction networks such as metabolic pathways. The BEST-KIT consists mainly consists of two kinds of modules, "MassAction" and "EnzymeKinetics.". In this study, we have developed a new module, "MassAction++, ", which can construct and analyze reaction schemes represented by both mass action law (mass balance) and approximated velocity functions of enzyme kinetics at steady state. All modules in BEST-KIT are developed in Java applet style, and can be carried outrun on the "any" platform machine through the web browser. The "MassAction++" module was developed by in Java applet style. andIt can save data related on to the constructed reaction scheme and time course data onto the client disk space and can load it onto the web browser.

【 授权许可】

Unknown