A Heuristic Algorithm for Plate SelectionThat Maximizes Compound Diversity

Croatica Chemica Acta

Klug-McLeod, Jacquelyn¹  Zhu, Hongyao¹  Bakken, Gregory A.¹ 

[1] Pfizer Worldwide Research and Development, Groton, Connecticut, United States

关键词: high throughput screening (HTS);    plate-based diverse subset (PBDS);    combinatorial optimization;   

DOI  :  

学科分类：化学（综合）

来源: Croatica Chemica Acta

【 摘 要 】

A heuristic algorithm was developed to maximize compound diversity within a subset of screening plates used in high throughput screening (HTS) to initiate the drug discovery process. The approach overcame the challenge of combinatorial...

【 授权许可】

Unknown