Assessment of Trabecular Bone Mineral Density Using Quantitative Computed Tomography in Normal Cats

Journal of Veterinary Medical Science

Donghoon LEE³  Dongwoo CHANG³  Jinhwa CHANG³  Wooshin CHOI³  Juhyung KIM³  Haengbok CHEON³  Ji-Houn KANG¹  Youngjae LEE³  Kijeong NA² 

[1] Laboratory of Internal Medicine, College of Veterinary Medicine, Chungbuk National University, Cheongju, Chungbuk 361-763, Republic of Korea;Laboratory of Clinical Pathology, College of Veterinary Medicine, Chungbuk National University, Cheongju, Chungbuk 361-763, Republic of Korea;Laboratory of Medical Imaging, College of Veterinary Medicine, Chungbuk National University, Cheongju, Chungbuk 361-763, Republic of Korea

关键词: bone mineral density;    feline;    quantitative computed tomography;    trabecular bone;   

DOI  :  10.1292/jvms.11-0579

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(30)Cited-By(5)The aim of this study was to assess age-related changes and anatomic variation in trabecular bone mineral density (tBMD) using quantitative computed tomography (QCT) in normal cats. Seventeen normal cats were included in this study and divided into the following 3 age groups:6 years (n=3). A computed tomographic scan of each vertebra from the 12th thoracic to the 7th lumbar spine and the pelvis was performed with a bone-density phantom (50, 100 and 150 mg/cm3, calcium hydroxyapatite, CIRS phantom®). On the central transverse section, the elliptical region of interest (ROI) was drawn to measure the mean Hounsfield unit (HU) value. Those values were converted to equivalent tBMD (mg/cm3) by use of the bone-density phantom and linear regression analysis (r2 >0.95). The mean tBMD value of the thoracic vertebrae (369.4 ± 31.8 mg/cm3) was significantly higher than that of the lumbar vertebrae (285 ± 58.1 mg/cm3). The maximum tBMD occurred at the T12, T13 and L1 levels in all age groups. There was a statistically significant difference in the mean tBMD value among the 3 age groups at the T12 (PPP=0.013), respectively. The present study suggests that age-related changes and anatomic variation in tBMD values should be considered when assessing tBMD using QCT in cats with bone disorders.

【 授权许可】

Unknown