Recurrent Sebaceous Carcinoma in an African Hedgehog (Atelerix albiventris)

Journal of Veterinary Medical Science

Yong-Baek KIM¹  Jun-Won PARK³  Eun-Ok KIM²  Hyung-Jin KIM³  Dae-Yong KIM³  Byoung-Yong LIM⁴  Won-Seok OH² 

[1] Department of Population Health and Pathobiology, The College of Veterinary Medicine, North Carolina State University;NeoDin Veterinary Science Institute;Department of Veterinary Pathology, College of Veterinary Medicine, Seoul National University;Garam Animal Clinic Seoul

关键词: hedgehog;    immunohistochemistry;    neoplasm;    sebaceous carcinoma;   

DOI  :  10.1292/jvms.09-0521

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(10)Cited-By(2)A 1.5-year-old intact male African hedgehog (Atelerix albiventris) was presented with a firm, non-movable subcutaneous mass on ventral chest area. Microscopically, the tumor was un-encapsulated, invasive up to the muscle layer, and composed of highly pleomorphic polygonal cells arranged in variably-sized lobules. The neoplastic cells had abundant cytoplasm with vacuolation and a large pleomorphic nucleus with prominent nucleoli. Mitotic figures were frequently observed with atypical mitoses. Immunohistochemically, the neoplastic cells were strongly positive for cytokeratin, but negative for vimentin. Based on these findings, a diagnosis of sebaceous carcinoma was made. Three months after the surgery, a recurrent mass was found at the surgical site. On necropsy, the mass has penetrated the underlying intercostal musculature, without metastasis to distant organs. This is the first report of a sebaceous carcinoma in an African hedgehog.

【 授权许可】

Unknown