Associations between growth hormone gene polymorphism and weight traits in Nellore bovines

Revista Brasileira de Zootecnia

Freitas, Alfredo Ribeiro de²  Josahkian, Luiz Antonio³  Cordeiro, Célia Maria Torres¹  Barreto, Cristine Chaves¹  Unanian, Maria Marina¹ 

[1] EMBRAPA, Brasília;EMBRAPA, São Carlos;ABCZ, Uberaba

关键词: bovine;    growth hormone gene;    weight;    Nellore breed     IntroduçãoOs marcadores de DNA tornaram-se;    na última década;    importantes para identificação de animais portadores de doenças genéticas e do parentesco;    além de características de produção de interesse econômico;   

DOI  :  10.1590/S1516-35982000000500016

学科分类：兽医学

来源: Universidade Federal de Vicosa

【 摘 要 】

- The polymorphism of the growth hormone gene (bGH) was studied in 211 Nellore pure breed bovine males to estimate the genotype and allelic frequencies and possible associations of the gene with weight traits. For this study, body weight data were collected at birth, weaning and monthly from 10 to 16 months of age. Additionally, weight gains from birth to weaning and weaning to 16 months of age were calculated. DNA was extracted from blood samples and the animals genotyped for Msp I (bGH/Msp I, 891 bp), Hae III (bGH/Hae III, 441 bp) and Alu I (bGH/Alu I, 427 bp) polymorphic sites. Every polymorphism presented two alleles. The predominant alleles were D, F and A, respectively. The effect of the bGH/Alu I AA genotype was observed on the weight gain from weaning to 15 months of age, and of the bGH/Msp I DD genotype from weaning to 14 and 15 months. The results suggest that bGH/Alu I and bGH/Msp I polymorphisms may be potential markers for the weight gain trait in young bulls.

【 授权许可】

CC BY-NC