Exercise-induced collapse in a Labrador Retriever

Ciência Rural

Palumbo, Mariana Isa Poci²  Araújo Júnior, João Pessoa¹  Basso, Roberta Martins²  Zakia, Luiza Stachewski²  Borges, Alexandre Secorun¹  Oliveira-Filho, José Paes de² 

[1] Unesp, Botucatu, Brasil;Universidade Estadual Paulista Júlio de Mesquita Filho, Botucatu, Brasil

关键词: exercise;    mutation;    dogs;    sequencing;    DNM1O colapso induzido pelo exercício (EIC) é uma enfermidade hereditária autossômica recessiva diagnosticada com maior frequência em cães da raça Labrador Retriever (TAYLOR et al;   

DOI  :  10.1590/0103-8478cr20131549

学科分类：农业科学（综合）

来源: Universidade Federal de Santa Maria * Centro de Ciencias Rurais

【 摘 要 】

The exercise-induced collapse (EIC) is a hereditary disease characterized by muscle weakness, impaired locomotion and collapse after intense exercise. This autossomic recessive disorder affects mainly Labrador Retriever presenting the mutation c.767G>T in the dynamin 1 (DNM1) gene. The objective of this study is to report the first case of exercise-induced collapse in Labrador Retriever in Brazil. The molecular test detected the specific genetic mutation and confirmed the clinical diagnosis in a Labrador Retriever with clinical history of weakness and collapse after exercise. It is important to include this disease as part of the differential diagnosis of neuromuscular diseases in Labrador Retriever and use the molecular test to guide matings.

【 授权许可】

Unknown