Outbreak of Febrile Respiratory Illness Caused by Adenovirus at a South Korean Military Training Facility: Clinical and Radiological Characteristics of Adenovirus Pneumonia

Japanese Journal of Infectious Diseases

You-In Yang³  Hee-Kyeong Lee¹  Se-Min Hwang⁴  Min-Jeong Kim⁴  Byung-Chul Chun⁴  Dong-Ean Park²  Sung-Jin Park³ 

[1] The Army Armed Forces Capital Hospital;Department of Preventive Medicine, Armed Forces Medical Command;The Armed Forces Il Dong Hospital;Department of Epidemiology Public Health Informatics, Korea University College, Korea University School of Public Health

关键词: adenovirus;    febrile respiratory illness;    pneumonia;    risk factor;   

DOI  :  10.7883/yoken.66.359

学科分类：传染病学

来源: National Institute of Infectious Diseases

【 摘 要 】

References(30)Cited-By(5)Adenovirus often causes respiratory disease outbreaks in military training soldiers. Compared with adenovirus pneumonia in young military adults, symptoms arising from febrile respiratory illness (FRI) caused by adenovirus have not been previously evaluated in Korean soldiers. We conducted an event-based outbreak investigation involving 712 male soldiers aged 19 to 21 years from March 14 to 30, 2012 to evaluate the epidemiological and clinical characteristics of patients with pneumonia and FRI caused by adenovirus. We described the laboratory and radiological characteristics of patients with adenovirus pneumonia. Among these, 407 cases of FRI and 15 cases of pneumonia were identified through active surveillance (attack rate of FRI, 57.16%; attack rate of pneumonia, 2.11%). Fire training and march training may present environmental risk factors for adenovirus-associated outbreaks. Most symptoms were mild. The most frequent symptom in patients with pneumonia and FRI was cough. Patients with pneumonia were associated with an increased incidence of dizziness (crude odds ratio [cOR], 9.65; 95% confidence interval [CI], 2.38–37.15) and a decreased incidence of rhinorrhea (cOR, 0.15; 95% CI, 0.04–0.53) during adenovirus-associated outbreaks. Differential leukocyte count revealed high monocytes, low lymphocytes, and low eosinophils, and chest computed tomography revealed a consolidation pattern and right lobar pneumonia. These findings warrant a high level of suspicion for adenovirus pneumonia.

【 授权许可】

Unknown