Relation between Erythrocyte Reduced Glutathione and Glutamate Concentrations in Korean Jindo Dogs with Erythrocytes Possessing Hereditary High Activity of Na-K-ATPase and a High Concentration of Potassium

Journal of Veterinary Medical Science

Motoshi TAJIMA¹  Yoshimitsu MAEDE¹  Hye-Sook CHANG²  Keun-Woo LEE²  Osamu YAMATO¹ 

[1] Laboratory of Internal Medicine, Department of Veterinary Clinical Sciences, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo 060-0818, Japan;College of Veterinary Medicine, Kyungpook National University, Taegu 702-701, Korea

关键词: canine erythrocyte;    Jindo dog;    reduced glutathione;   

DOI  :  10.1292/jvms.61.1179

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(23)Cited-By(5)The concentrations of sodium, potassium, reduced glutathione (GSH) and free amino acids and Na-K-ATPase activity in erythrocytes were examined in 35 purebred Jindo dogs in Korea. The incidence of Jindo dogs with a high potassium concentration and high activity of Na-K-ATPase in erythrocytes (HK phenotype) was 25.7%. The erythrocyte GSH concentration in HK Jindo dogs varied widely, from 2.45 to 12.38 mmol/l of RBCs, and was positively correlated with the erythrocyte glutamate concentration. These results indicate that HK Jindo dogs have normal to very high levels of erythrocyte GSH, which might result from the varying quantity of Na-dependent glutamate influx in the erythrocytes.

【 授权许可】

Unknown