Effects of Perineural Capsaicin Treatment on Compound Action Potentials of Superior Laryngeal Nerve Afferents in Sevoflurane-Anesthetized Dogs

Journal of Veterinary Medical Science

Arata KANAMARU²  Kentaro KOJIMA³  Nobuo SASAKI³  Ryohei NISHIMURA³  Hirokazu TSUBONE²  Tatsushi MUTOH¹ 

[1] Division of Cardiovascular Medicine and Department of Pediatrics, University of California, Davis, CA 95616, USA.;Department Comparative Pathophysiology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-8657, Japan;Department of Veterinary Surgery, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-8657, Japan

关键词: canine;    conduction velocity;    laryngeal C-fiber;   

DOI  :  10.1292/jvms.62.117

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(15)Cited-By(3)Effects of perineural capsaicin (CAPS) treatment on compound action potentials of the superior laryngeal nerve (SLN) afferents were studied in 6 sevoflurane-anesthetized dogs. Perineural CAPS (100 μg/ml) to the bilateral SLNs reduced (P<0.01) the peak and integral amplitudes of the C-wave of the compound action potential. By contrast, the perineural CAPS had no effect on the A-wave component (P>0.05). Removal of the perineural CAPS recovered the C-wave to pretreatment level. The perineural CAPS treatment selectively blocks C-wave compound action potentials of the SLN afferents, providing a useful tool for studies of laryngeal C-fibers in respiratory physiology.

【 授权许可】

Unknown