Chikungunya Fever in Japan Imported from the Caribbean Islands

Japanese Journal of Infectious Diseases

Aoi Mitarai³  Satoru Miyake³  Yasushi Miyahira⁴  Yukiko Kobayashi¹  Koki Kaku²  Kazuo Imai⁵  Takuya Maeda⁵  Akihiko Kawana⁵  Eri Nakayama¹  Kei Mikita⁵  Yasuko Honma³ 

[1] Department of Virology 1, National Institute of Infectious Diseases;National Defense Medical Research Institute, Department of Infectious Disease Epidemiology Analysis and Response Officer;Narita Airport Quarantine Station;Department of Global Infectious Diseases and Tropical Medicine, National Defense Medical College;Division of Infectious Diseases and Pulmonary Medicine, National Defense Medical College

关键词: Chikungunya virus;    Caribbean;    Japan;    Chikungunya fever;   

DOI  :  10.7883/yoken.JJID.2015.063

学科分类：传染病学

来源: National Institute of Infectious Diseases

【 摘 要 】

References(17)Cited-By(2)A 53-year-old Japanese woman who was working as a volunteer in the Commonwealth of Dominica in the Caribbean islands presented with a high-grade fever and severe incapacitating generalized arthralgia. The Asian genotype of the chikungunya virus was confirmed using reverse transcription-PCR and serology, based on the presence of a specific neutralization titer and immunoglobulin M antibodies. She was diagnosed with post-chikungunya chronic arthritis based on persistence of her polyarthritis for 3 months and the presence of rheumatoid factor, immunoglobulin G-rheumatoid factor, and matrix metalloproteinase-3. Chikungunya virus should be considered as a causative pathogen in travelers returning from Caribbean islands. Clinicians should consider chikungunya fever in the differential diagnosis of patients who complain of chronic arthritis and have a history of travel to an endemic area.

【 授权许可】

Unknown