Prevalence of Hepatitis E Virus (HEV) Infection in Wild Boars (Sus scrofa leucomystax) and Pigs in Gunma Prefecture, Japan

Journal of Veterinary Medical Science

Masataka SHIONO¹  Yurie SATO-MOTOI¹  Toshio NOBUSAWA¹  Toshie MOKUDAI¹  Yukio MORITA⁵  Hirokazu KIMURA²  Soichi MARUYAMA⁴  Akira NAGAI⁵  Akiyo NODA¹  Hiroyuki SAKANIWA³  Yoko YOKOTA¹  Hiroshi SATO²  Chieko SAKANO¹  Shigeki YAMAMOTO⁶  Hidenori KABEYA⁴ 

[1] Gunma Prefectural Meat Inspection Laboratory;National Institute of Infectious Disease;Gunma Prefectural Governmental Office, Natural Environmental Division;Department of Veterinary Medicine, College of Bioresource Science, Nihon University;Gunma Prefectural Institute of Public Health and Environmental Sciences;National Institute of Health Sciences

关键词: hepatitis E virus;    Japan;    swine;    wild boar;   

DOI  :  10.1292/jvms.71.21

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(31)Cited-By(12)The prevalence of hepatitis E virus (HEV) infection in wild boars and pigs in Gunma Prefecture, Japan, was serologically and genetically examined. The positive detection rates of anti-HEV IgG and HEV RNA in the wild boars were 4.5% (4/89) and 1.1% (1/89), whereas those in the pigs were 74.6% (126/169) and 1.8% (3/169), respectively. The positive rates of anti-HEV IgG and HEV RNA on the 17 pig farms in the present study ranged from 20% to 100%, respectively. One male wild boar approximately 5 years of age was positive for HEV RNA but was negative for anti-HEV IgG. Three pigs from 2 farms were positive for HEV RNA; 2 of these pigs were negative for HEV IgG, and the other was positive. A phylogenetic analysis revealed that all of the HEV ORF1 genes detected in the present study belonged to genotype III. In Gunma Prefecture, HEV is highly prevalent and widespread, and uncooked wild boar and pig meat may have the potential to transmit HEV to humans.

【 授权许可】

Unknown