Feline Epidermal Nevi Resembling Human Inflammatory Linear Verrucous Epidermal Nevus

Journal of Veterinary Medical Science

Koji NISHIFUJI³  Kazuhiro KARIYA⁴  Miyuki ITOH¹  Masafumi SATO⁴  Junichi KAMIIE²  Yoshiyasu KOBAYASHI¹  Kinji SHIROTA²  Munetaka MATSUMOTO⁴ 

[1] Laboratory of Veterinary Pathology, Division of Pathological Science, Department of Basic Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine, Inada-cho, Obihiro, Hokkaido 080–8555, Japan;Laboratory of Veterinary Pathology, School of Veterinary Medicine, Azabu University, 1–17–71 Fuchinobe, Chuo-Ku, Sagamihara, Kanagawa 252–5201, Japan;Laboratory of Veterinary Internal Medicine, Tokyo University of Agriculture and Technology, 3–5–8 Saiwai-cho, Fuchu, Tokyo 183–8509, Japan;AC Plaza Kariya Animal Hospital, 5–20–2 Morishita, Koto-ku, Tokyo 135–0004, Japan

关键词: dermatopathology;    feline;    nevus;    papilloma;    skin disease;   

DOI  :  10.1292/jvms.12-0117

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(12)Multiple, pigmented, verrucous, cutaneous lesions in a 2-year-old female cat were pathologically examined. The lesions were linearly arranged on the right side of the body, and had developed along with moderate pruritus since infancy. Histologically, prominent exophytic, papillomatous outgrowths of the epidermis and acanthosis with intense ortho and parakeratotic hyperkeratosis were characteristic of the lesions. Dermal inflammation with mononuclear cells, neutrophils, and eosinophils was also noted. Inclusion bodies, cellular degeneration, and intranuclear viral particles suggesting papillomavirus infection in the keratinocytes were not observed. Papillomavirus antigen and DNA were not detected in the lesions by immunohistochemistry and polymerase chain reaction, respectively. In accordance with these clinical and histopathological features, the cutaneous lesions of the present cat were diagnosed as epidermal nevi, which were consistent with human inflammatory linear verrucous epidermal nevi.

【 授权许可】

Unknown