期刊论文详细信息
Journal of Veterinary Medical Science | |
Serum Resistance and Aerobactin Iron Uptake in Avian Escherichia coli Mediated by Conjugative 100-Megadalton Plasmid | |
Kazunori IKE1  Hirofumi DANBARA1  Katsumi KUME1  Kazuyoshi KAWAHARA1  | |
关键词: aerobactin; avian E. coli; iron uptake; serum resistance; virulence plasmid; | |
DOI : 10.1292/jvms.54.1091 | |
学科分类:兽医学 | |
来源: Japanese Society of Veterinary Science | |
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【 摘 要 】
References(43)Cited-By(12)A total of 115 strains of Escherichia coli isolated from chickens with colisepticemia in Japan were examined for chicken lethality and virulence factors. It was found that serum resistance and aerobactin-mediated iron uptake are the most prevalent characteristics in these strains. Among them, S-20, a representative virulent strain of serotype O2, was further studied. S-20 harbored a conjugative 100-megadalton (Mdal) plasmid, designated pKI100. Curing and reintroduction experiments showed that pKI100 encodes both serum resistance and aerobactin-mediated iron uptake, and the diminished virulence of the pKI100-cured strain was fully restored by the reintroduction of the plasmid. These results demonstrated that pKI100 is the virulence plasmid of the S-20 strain, and that serum resistance and aerobactin-mediated iron uptake are the virulence factors in E. coli strains which cause avian colibacillosis.【 授权许可】
Unknown
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