Superior thyroid artery mean peak systolic velocity for the diagnosis of thyrotoxicosis in Japanese patients

Endocrine Journal

Sayaka Kubo¹  Kageumi Takeno¹  Ken Sakai¹  Kousuke Azuma¹  Yoshio Fujitani¹  Masahiro Goto¹  Rei Kanno¹  Satomi Takahashi¹  Takahisa Hirose¹  Hirotaka Watada¹  Ryuzo Kawamori¹  Toyoyoshi Uchida¹ 

[1] Departments of Medicine, Metabolism and Endocrinology, Juntendo University, Graduate School, Tokyo, Japan

关键词: Thyroid artery;    Thyrotoxicosis;    Ultrasonography;    Graves’ disease;    Destructive thyroiditis;   

DOI  :  10.1507/endocrj.K09E-263

学科分类：内分泌与代谢学

来源: Japan Endocrine Society

【 摘 要 】

References(16)Cited-By(5)Thyrotoxicosis with diffuse thyroid disease can be caused by Graves’disease (GD) or destructive thyroiditis (DT). Optimal treatment of the underlying condition requires a prompt and accurate method for the diagnosis of thyrotoxicosis. This study evaluated measurement of the mean peak systolic velocity of the superior thyroid artery (STA-PSV) by ultrasonography in detecting thyrotoxicosis in Japanese patients. We recruited 44 patients with untreated GD, 13 with DT, 55 with treated GD, and 49 subjects without thyroid disease. Blood samples were taken to analyze thyroid function and STA-PSV was measured by ultrasonography. The mean STA-PSV was the highest in the untreated GD group, followed by treated GD patients and then those with DT. Receiver operating characteristic curves of the STA-PSV values demonstrated that the area under the curve required discriminating untreated GD from DT was 0.941. The optimal sensitivity and specificity were 83.7% and 92.3%, respectively, using 45 cm/sec as the cutoff value. In conclusion measurement of STA-PSV by ultrasonography is useful for the diagnosis of thyrotoxicosis in Japanese patients.

【 授权许可】

Unknown