Predictive value of antimicrobial susceptibility from previous urinary tract infection in the treatment of re-infection

British Journal of General Practice

Belinda Hanahoe¹  Martin Cormican¹  Akke Vellinga¹  Andrew W Murphy¹ 

[1] Discipline of General Practice, School of Medicine, NUI Galway, Ireland

关键词: antibiotic resistance;    Escherichia coli;    general practice;    predictive value;    urinary tract infection;   

DOI  :  10.3399/bjgp10X514765

学科分类：卫生学

来源: Royal College of General Practitioners

【 摘 要 】

Recurrent urinary tract infections are often re-infections; therefore, antimicrobial susceptibility test results from a previous episode may guide the empiric therapy in subsequent episodes. This analysis provides predictive values of the antimicrobial susceptibility of previous Escherichia coli isolates for the treatment of re-infections in routine clinical practice. If resistance to ampicillin, trimethoprim, or ciprofloxacin is detected, re-prescription within 3 months is imprudent. Susceptibility to nitrofurantoin, ciprofloxacin, or trimethoprim in a previous sample supports their prescription for a re-infection within 3 months and up to a year. Resistance to nitrofurantoin is low and, once detected, decays relatively quickly. Nitrofurantoin should be considered as a first-line agent for initial and repeat treatment.

【 授权许可】

Unknown