Kinetic Analysis of T Cells and Antibody Production in Chickens Infected with Marek's Disease Virus

Journal of Veterinary Medical Science

Masakazu HATTORI¹  Kazuhiko OHASHI¹  Misao ONUMA¹  Hideaki YAMAMOTO¹  Chihiro SUGIMOTO¹ 

关键词: helper T cell;    Marek's disease virus;   

DOI  :  10.1292/jvms.57.945

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(15)Cited-By(1)In chickens inoculated with a Marek's disease (MD) vaccine and subsequently with virulent MD virus (MDV), CD4+ T cell population was drastically decreased following a transient increase at 21 days after hatching (16 days after MDV infection). To elucidate the immune response after the decrease of CD4+ T cell population, the antibody production against sheep red blood cells (SRBC) was examined in these chickens. Chickens challenged with a virulent MDV after MD vaccination produced lower titers of anti-SRBC antibody than untreated control chickens. Antibody production against SRBC was also lowered in vaccinated chickens or chickens challenged with a virulent MDV.

【 授权许可】

Unknown