Tumor Bed Boost Integration during Whole Breast Radiotherapy: A Review of the Current Evidence

Breast care

Pierfrancesco Franco¹  Giuseppe Girelli¹  Umberto Ricardi¹  Piera Sciacero¹  Domenico Cante¹  Maria Rosa La Porta¹ 

[1] aDepartment of Oncology, Radiation Oncology, University of Torino, Turin, Italy

关键词: Adjuvant whole breast radiotherapy;    Concomitant boost;    IMRT;    IGRT;    Hypofractionation;    Simultaneous integrated boost;    Breast cancer;   

DOI  :  10.1159/000369845

学科分类：泌尿医学

来源: S Karger AG

【 摘 要 】

Radiation therapy delivered with hypofractionation, which involves the delivery of a higher dose per fraction in fewer fractions (generally with a lower total nominal dose) over a shorter overall treatment time, is an established therapeutic option at least for a selected group of early breast cancer patients after breast-conserving surgery. Optimal delivery of the tumor bed boost dose in terms of timing, fractionation, and total dose whenever a hypofractionated schedule is employed has yet to be established. We herein present a review of the current evidence on the role of boost integration in whole breast radiotherapy.

【 授权许可】

Unknown