Seroprevalence of Hepatitis B virus infection in a Brazilian jail

Revista Brasileira de Epidemiologia

Coelho, Harnoldo Colares¹  Passos, Afonso Dinis Costa¹  Oliveira, Maria de Lourdes Aguiar²  Perdoná, Gleici Castro¹  Figueiredo, José Fernando de Castro¹  Miguel, Juliana Custódio²  Oliveira, Sabrina Alberti Nóbrega de² 

[1] Universidade de São Paulo;FIOCRUZ

关键词: Hepatitis B;    Prisons;    Prevalence;    Risk fators;   

DOI  :  10.1590/S1415-790X2009000200003

学科分类：过敏症与临床免疫学

来源: SciELO

【 摘 要 】

This survey aimedto estimate the prevalence of HBV serological markers and risk factors for thisinfection in male inmates at the Penitentiary of Ribeirão Preto, Stateof São Paulo, Brazil. Out of 1030 inmates, a simple random sample of333 participants answered a questionnaire and had blood samples collected, fromMay to August 2003. Enzyme-linked immunosorbent assay (ELISA) was used to diagnoseHBV infection (HBsAg, anti-HBsAg, and total anti-HBc). The overall prevalencefor HBV markers in inmates was 19.5% (CI_95%: 15.2 - 23.8). The participants'mean age was 30.1 years. In univariate analysis, HBV infection was associatedwith age > 30 years (p<0.001), previous injecting drug use (p<0.001)and previous sharing of needles (p<0.001). In a logistic regression multivariatemodel, HBV infection was associated with age > 30 years (OR = 3.3; CI_95%:1.8 - 6.1) and previous injecting drug use (OR = 2.7; CI_95%: 1.9- 6.4). HBV infection on prisons represents a major health problem, mainly associatedwith age over 30 years and previous injecting drug use.

【 授权许可】

CC BY