Specific immune response of cattle to experimental sensibilization by inactivated Mycobacterium bovis and Mycobacterium avium

Pesquisa Veterinária Brasileira

Jorge, Klaudia S.G.¹  Almeida, Robson F.C.³  Fernandes, Marta C.³  Osório, Ana Luiza A.R.¹  Soares, Cleber O.⁴  Carvalho, Nilton M.²  Madruga, Claudio R.⁴ 

[1] UFMS;UFMS, Campo Grande;Universidade Federal de Mato Grosso do Sul;Embrapa Gado de Corte, Campo Grande

关键词: Mycobacterium bovis;    Mycobacterium avium;    gamma-interferon;    tuberculin;    immune response.;   

DOI  :  10.1590/S0100-736X2006000400002

来源: Colegio Brasileiro de Patologia Animal-CBPA

【 摘 要 】

The presumptive diagnosis of bovine tuberculosis is based on analysis of the immune response to micobacterial antigens. This experimental simulation of sensibilization by Mycobacterium bovis and Mycobacterium avium in cattle aimed to verify the immune response by both the cervical comparative test and the evolution of the specific production of gamma-interferon, and also to identify interference of unspecified reactions by M. avium on the test results. The results support that the experimental animals started a response of delayed hypersensitivity to the inactivated bacilli, and that both diagnostic tests for bovine tuberculosis were efficient for the identification of animals sensitized with M. bovis and for discrimination of reactions generated by inoculation of cattle with M. avium. Index

【 授权许可】

CC BY-NC