Comparison of the Upper Gastrointestinal Effects of Etodolac and Aspirin in Healthy Dogs

Journal of Veterinary Medical Science

Takashi KANNO¹  Katsuaki NISHIHARA²  Takao SARASHINA²  Yuji UZUKA²  Shigeyuki TANABE²  Hiroto KIKUCHI¹ 

[1] The Second Group of Research Center, Nippon Beet Sugar MFG., Co., Ltd.;Laboratory of Veterinary Internal Medicine, Obihiro University of Agriculture and Veterinary Medicine

关键词: canine;    etodolac;    gastric lesion;   

DOI  :  10.1292/jvms.63.1131

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(11)Cited-By(8)Fifteen healthy castrated male dogs were separated into three treatment groups that were administered etodolac, aspirin and a placebo orally, respectively. All treatments were continued for 28 days. The animals were examined endoscopically on days 0, 3, 7, 10, 14, 17, 21, 24 and 28. There were no gastrointestinal mucosal lesions in either the etodolac or the placebo group, whereas some gastric lesions developed in the aspirin group after day 17. We considered that etodolac could be used for long-term treatments in dogs with fewer side-effects on the gastric mucosa than aspirin.

【 授权许可】

Unknown