The Novel Ketoprofenamides: Synthesis and Spectroscopic Characterization

Croatica Chemica Acta

Jadrijević-Mladar Takač, Milena¹  Metelko, Biserka²  Novak, Predrag²  Zorc, Branka¹  Zovko, Marijana¹ 

[1] Faculty of Pharmacy and Biochemistry, A. Kovačića 1, 10 000 Zagreb, Croatia;PLIVA Pharm. Ind. Inc., Research Division, Prilaz baruna Filipovića 25, 10 000 Zagreb, Croatia

关键词: ketoprofen;    amide;    benzotriazole;    synthesis;    FTIR and NMR spectroscopy;   

DOI  :  

学科分类：化学（综合）

来源: Croatica Chemica Acta

【 摘 要 】

Synthesis of a series of new ketoprofenamides ( 3a-h ) is described. Amide formation was achieved by aminolysis of ketoprofen benzotriazolide ( 2 ) with various amines: primary, secondary, hydroxylamine and amino acid β-alanine. The...

【 授权许可】

Unknown