Induction of Primer Pheromone Production by Dihydrotestosterone in the Male Goat

Journal of Veterinary Medical Science

Takehumi KIKUSUI¹  Eri IWATA¹  Yuji MORI¹  Yoshihiro WAKABAYASHI¹  Souichiro MATSUSE¹  Yukari TAKEUCHI¹ 

[1] Laboratory of Veterinary Ethology, The University of Tokyo

关键词: caprine;    dihydrotestosterone;    pheromone;   

DOI  :  10.1292/jvms.63.347

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(16)Cited-By(11)Castrated goats were treated with dihydrotestosterone (DHT) for four weeks. Skin samples were collected from the head and the rump regions before and after the DHT treatment. The primer pheromone activities of these samples were assessed neurophysiologically by recording electrophysiological manifestations of the hypothalamic gonadotropin-releasing hormone (GnRH) pulse generator activity. Pheromone activity was detected in both the head and rump skin samples following the DHT treatment, although the development of sebaceous glands was limited to the head region. Taken together with our previous finding that testosterone treatment results in the appearance of primer pheromone activity in the skin sample of the head region but not of the rump region, these observations suggests that the regional difference of pheromone production would be ascribed to intrinsic expression levels of 5α-reductase, an enzyme converting testosterone to DHT.

【 授权许可】

Unknown