Genome Editing Tools for Functional Analysis of HNF1A and IL6ST Genes

Croatica Chemica Acta

Bočkor, Luka¹  Vojta, Aleksandar¹  Zoldoš, Vlatka¹  Markulin, Dora¹  Tremski, Mihaela¹  Dobrinić, Paula¹  Tadić, Vanja¹ 

[1] University of Zagreb, Faculty of Science, Department of Biology, Division of Molecular Biology, Horvatovac 102a, HR-10000 Zagreb, Croatia

关键词: gene knockout;    TALEN;    CRISPR;    HNF1A;    IL6ST;    genome editing;   

DOI  :  

学科分类：化学（综合）

来源: Croatica Chemica Acta

【 摘 要 】

Genome editing tools, such as TALEN (transcription activator-like effector nuclease) or CRISPR-Cas9 (CRISPR-associated protein-9 nuclease) systems, enable functional studies by targeted gene knockout. They introduce double-stranded...

【 授权许可】

Unknown