Experimental Transplantation Models of Mouse Sarcoma 180 in ICR Mice for Evaluation of Anti-Tumor Drugs

Journal of Veterinary Medical Science

Masataka SHIRAI¹  Hiroko IZUMI¹  Tetsuji YAMAGAMI¹ 

关键词: cervicodorsal hypoderm;    intravenous transplantation;    lung tumorigenesis method;    mouse sarcoma 180;    solid tumor;   

DOI  :  10.1292/jvms.53.707

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(12)Cited-By(3)Two new experimental models of transplantable mouse sarcoma 180 were developed in ICR mice in order to examine the optimum transplantation sites and methods. The cervicodorsal hypoderm was evaluated as the best transplantation site for mouse sarcoma 180 among seemingly usable transplantation sites such as groin, armpit, cervicodorsal, abdominal and lumbodorsal hypoderms by hypodermic transplantation. In addition, the lung transplantation model was established by monitoring the survival period as a reliable parameter for evaluation of anti-tumor effects.

【 授权许可】

Unknown