Influence of the Acyl Moiety on the Hydrolysis of Quinuclidinium Esters Catalyzed by Butyrylcholinesterase

Croatica Chemica Acta

Tomić, Srđanka¹  Primožič, Ines¹ 

[1] Department of Chemistry, Faculty of Science, University of Zagreb Horvatovac 102a, HR-10000 Zagreb, Croatia

关键词: esters of quinuclidin-3-ol;    enzymic resolution;    butyrylcholinesterase;    hydrolysis kinetics;    inhibition constants;   

DOI  :  

学科分类：化学（综合）

来源: Croatica Chemica Acta

【 摘 要 】

Eight chiral esters of quinuclidin-3-ol and butyric, acetic, pivalic and benzoic acid were synthesized as well as their racemic and chiral, quaternary N-benzyl derivatives. All racemic and chiral quaternary compounds were studied as...

【 授权许可】

Unknown