In Search of Simplification: the Use of Topological Complexity Indices to Guide Retrosynthetic Analysis

Croatica Chemica Acta

Bertz, Steven H.¹  Rücker, Christoph² 

[1] Complexity Study Center, Mendham, NJ 07945, USA;Department of Mathematics, University of Bayreuth, D-95440 Bayreuth, Germany

关键词: bicyclo[2.2.1] heptane;    complexity indices;    disconnections;    retrosynthetic analysis;    simplification principles;    spiro [3.3] heptane;    ...;   

DOI  :  

学科分类：化学（综合）

来源: Croatica Chemica Acta

【 摘 要 】

Topological complexity indices N S , N T , N S (lpe), N T (lpe), twc and wcx are used to rank the one-bond disconnections of bicyclo[2.2.1]heptane, spiro[3.3]heptane and their aza derivatives with respect to the degree of simplification...

【 授权许可】

Unknown