‘They won't do any harm and might do some good’: time to think again on the use of antidepressants?

British Journal of General Practice

Hugh Middleton¹  Joanna Moncrieff¹ 

[1] School of Sociology and Social Policy, University of Nottingham, Nottingham

关键词: antidepressant;    depression;    efficacy;    placebo;    sick role;    side effects;   

DOI  :  10.3399/bjgp11X548983

学科分类：卫生学

来源: Royal College of General Practitioners

【 摘 要 】

Despite NICE guidance that should have limited it, antidepressant prescribing continues to increase. Research evidence suggests that much if not all of the observed efficacy should be attributed to complex non-specific effects rather than ‘restoration of disturbed brain chemistry’. According to this view the uncertain benefits of antidepressants are unlikely to outweigh the risks, suggesting the need to explore other approaches to treatment.

【 授权许可】

Unknown