A comparative study of selenium concentration and glutathione peroxidase activity in normal and breast cancer patients

Public Health Nutrition

Abdolreza Rajaei Fard¹  Masoumeh Moradi¹  Abdolrasoul Talei¹  Mohammad Hassan Eftekhari¹ 

关键词: Antioxidant;    Breast cancer;    Glutathione peroxidase;    Selenium;   

DOI  :  10.1017/S1368980008001924

学科分类：卫生学

来源: Cambridge University Press

【 摘 要 】

ObjectiveThe present study was undertaken to compare plasma Se values and glutathione peroxidase (GPX) activity in normal and breast cancer patients.DesignIn a case–control study, forty-five breast cancer patients and the same number of healthy women were randomly selected from their population. Se was measured in plasma by atomic absorption spectrophotometry and GPX activity in erythrocytes was measured using a standard spectrophotometric method.ResultsPlasma Se concentration in healthy women and breast cancer patients was in the normal range, with no statistically significant difference observed between the two groups (138·40 (sd 40·36) μg/l v. 132·15 (sd 35·37) μg/l, respectively). Erythrocyte GPX activity was significantly (P

【 授权许可】

Unknown