Nervous form of caprine arthritis-encephalitis

Ciência Rural

Pedroso, Pedro Miguel Ocampos³  Ximenes, Fábio Henrique Bezerra¹  Borges, José Renato Junqueira¹  Driemeier, David⁵  Castro, Márcio Botelho de¹  Guedes, Karla Moraes Rocha²  Melo, Cristiano Barros de⁴  Mustafa, Vanessa da Silva¹ 

[1] Universidade de Brasília (UnB), Brasília, Brasil;Universidade de Cuiabá (UNIC), Cuiabá, Brasil;Universidade Federal do Recôncavo da Bahia (UFRB), Cruz das Almas, Brasil;UnB, Brasília, Brasil;Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brasil

关键词: neurologic disease;    small ruminant lentiviruses;    leucoencephalomyelitis;   

DOI  :  

学科分类：农业科学（综合）

来源: Universidade Federal de Santa Maria * Centro de Ciencias Rurais

【 摘 要 】

Two cases are described of female goats, Saanen crossbreds, two months old, with clinical signs of hind limb paresis, incoordination, difficulty breathing and cachexia, which were subjected to euthanasia due to unfavorable prognosis. At necropsy it was possible to observe that there was congestion of the central nervous system (CNS) and pulmonary consolidation in both goats. Microscopic changes were characterized by multifocal lymphoplasmacytic leucoencephalomielitis, with vacuolization of neuropile and axonal spheroids, leptomeningitis, interstitial nonsupurative pneumonia in goat A and bacterial bronchopneumonia in goat B. Immunohistochemistry (IHC) was positive for the caprine arthritis - encephalitis virus in thalamus fragments. The agar gel immunodiffusion (AGID) test was performed in sera sample of twenty animals and sixteen resulted positive. Diagnosis of the nervous form of caprine arthritis-encephalitis virus (CAEV) infection was based on clinical and pathological status, IHC and AGID. This clinical presentation of CAE could be uncommon in Brazil, but must be considered in case of neurologic diseases in small ruminants.

【 授权许可】

CC BY-NC