Production of Monoclonal Antibodies against Classical Swine Fever Virus and Their Use for Antigenic Characterization of Japanese Isolates

Journal of Veterinary Medical Science

Tomoko NISHIMORI¹  Shunji YAMADA¹  Mitsugu SHIMIZU¹ 

关键词: antigenicity;    classical swine fever;    monoclonal antibody;   

DOI  :  10.1292/jvms.58.707

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(19)Cited-By(14)Twenty monoclonal antibodies (MAbs) were produced against the virulent ALD or vaccinal GPE strains of classical swine fever (CSF) virus. The MAbs were divided into 7 groups on the basis of the difference in the reaction spectrum to various CSF and bovine viral diarrhea-mucosal disease (BVD-MD) viruses. The panel of the MAbs could classify 20 CSF viruses into 6 types, and could discriminate between not only CSF and BVD-MD viruses but also the vaccinal GPE strain and the field isolates of CSF virus. The results indicated that the MAbs were useful for diagnosis and investigation of CSF viruses.

【 授权许可】

Unknown