Pemphigus Foliaceus with Typical Histological and Immunohistological Findings in a Dog

Journal of Veterinary Medical Science

Syouji WADA¹  Kyoko SHINYA¹  Hiroshi MORIOKA¹  Takashi UMEMURA¹  Kohji NOMURA¹ 

关键词: canine;    direct immunohistological examination;    pemphigus foliaceus;   

DOI  :  10.1292/jvms.58.815

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(11)Cited-By(2)A seven-year-old female mongrel dog showed incurable skin lesions for about a year. The lesions were at nasal bridge and periocular area, and were composed of crust formation and scaling. Biopsy specimens from the skin lesions possessed with multiple intraepidermal pustules containing many acantholytic keratinocytes. Direct immunoperoxidase stain using paraffin-embedded section showcd IgG deposition at the intercellular area of upper epidermis and follicular infundibula. IgG was not detected at basement membrane zone. Clinical and pathological findings of the present case were identical to those of pemphigus foliaceus, an uncommon pustular autoimmune skin disease.

【 授权许可】

Unknown