Synthesis, Crystal Structure and in vitro DNA Binding Studies of Combretastatin A-4 Analogue

Croatica Chemica Acta

Rizvi, Masood Ahmad³  Yaseen, Zahid²  Gupta, Vivek¹  Dangat, Yuvraj⁴  Khan, Khaliquz Zaman³ 

[1] Department of Physics, University of Jammu, Babasaheb Ambedkar Road, New Campus, Jammu Tawi - 180 006, J&K, India;Department of Civil Engineering, Islamic University of Science and Technology, Kashmir 192122, India;Department of Chemistry, University of Kashmir, Hazratbal Srinagar,190006, J&K, India;Physical Chemistry Division, CSIR-National Chemical Laboratory, Pune - 411008, India

关键词: crystal structure;    DNA binding;    combretastatin A-4;    benzil;    bio-physical;    phenazones;    fluorescence;    ethidium bromide;   

DOI  :  

学科分类：化学（综合）

来源: Croatica Chemica Acta

【 摘 要 】

Synthesis of a novel Combretastatin A-4 analogue using Schiff’s reaction of benzil and 4-aminoantipyrine has been achieved under solvent free conditions. The structure of compound was examined spectroscopically and confirmed from...

【 授权许可】

Unknown