Diet and cancer: where are we and where are we going?

Proceedings of the Nutrition Society

Gad Rennert¹ 

关键词: Cancer risk;    Dietary intervention studies;    Genetic susceptibility;    Gene-diet interactions;   

DOI  :  10.1079/PNS2002237

学科分类：卫生学

来源: Cambridge University Press

【 摘 要 】

Many studies have shown that overall dietary patterns, dietary components consumed, or mode of food preparation are all possibly relevant in either reducing or increasing the risk of cancer in animals or man. Yet, dietary intervention studies, stemming from laboratory and epidemiological observational studies have often failed to demonstrate the anticipated protection against cancer. One possible explanation for the discrepancy between the results of various observational and experimental chemo-prevention studies is the lack of control for biological diversity of the participants of these studies. It is suggested that future epidemiological studies provide evidence stratified by status of major metabolic polymorphisms pertinent to the study subject, and that future intervention studies take these differences into account in the design and analysis phases.

【 授权许可】

Unknown