Respiratory virus infections among hospitalized patients with suspected influenza A H1N1 2009 virus during the first pandemic wave in Brazil

Brazilian Journal of Infectious Diseases

Bellei, Nancy²  Moreira, Luciana¹  Carraro, Emerson¹  Guatura, Sandra²  Watanabe, Aripuanã Sakurada Aranha¹  Sinohara, Juliana¹  Camargo, Clarice¹  Granato, Celso²  Puerari, Diane¹ 

[1] Universidade Federal de São Paulo, São Paulo, Brazil;Unifesp, São Paulo, Brazil

关键词: influenza virus;    influenza A H1N1 2009 virus;    rhinovirus;    human metapneumovirus;    human respiratory syncytial virus;    respiratory viruses.;   

DOI  :  10.1590/S1413-86702011000300007

来源: Contexto

【 摘 要 】

INTRODUCTION: During the first pandemic wave of the influenza A H1N1 2009 virus, morbidity was particularly high in Brazil. Hospitalizations resulting from severe respiratory disease due to suspected influenza-like illness created an opportunity to identify other respiratory viruses causing lower respiratory infections.
OBJECTIVE: The purpose of this study was to assess viral etiologies among samples collected during the first pandemic wave of H1N1 2009 from hospitalized patients with suspected cases in a Brazilian Sentinel Hospital.
PATIENTS AND METHODS: Viral etiologies were investigated in samples from 98 children and 61 adults with fever, cough and dyspnea who were admitted to São Paulo Sentinel Hospital with suspected H1N1 infection.
RESULTS: From August to November 2009, in 19.5% (31/159) of the samples 2009 H1N1 virus was detected with 23% (14/61) in adults (median age 25 years, range: 14-55 years) and 18.4% (17/92) in children (median age 5 years, range: 4 months - 11 years). Among the negative samples, a wide range of causative etiologic agents was identified. Human rhinovirus was the most frequent virus (23.91%) in children and human metapneumovirus (11.48%) was the second most frequent in adults, following 2009 H1N1 virus (22.95%).
CONCLUSION: These data highlight the need to diagnose other viral infections that can co-circulate with influenza and may have been neglected by physicians as causes of severe respiratory diseases.

【 授权许可】

CC BY-NC-ND