Synthesis of Novel Aliphatic N-sulfonylamidino Thymine Derivatives by Cu(I)-catalyzed Three-component Coupling Reaction

Croatica Chemica Acta

Ismaili, Hamit⁴  Glavaš-Obrovac, Ljubica³  Žinić, Biserka⁵  Bajić, Miroslav²  Krstulović, Luka²  Višnjevac, Aleksandar¹ 

[1] Division of Physical Chemistry, Ruđer Bošković Institute, Bijenička cesta 54, HR-10000 Zagreb, Croatia;Faculty of Veterinary Medicine, University of Zagreb, Heinzelova 55, HR-10000 Zagreb, Croatia;Department of Clinical Chemistry and Biochemistry, School of Medicine, J. J. Strossmayer University of Osijek, Huttlerova 4, HR-31000 Osijek, Croatia;Clinical Hospital Centre Osijek, Clinical Institute of Nuclear Medicine and Radiation Protection, Huttler;Faculty of Mathematics and Natural Sciences, University of Pristina, Agim Ramadani n.n. 10000, Pristina, Kosovo;Division of Organic Chemistry and Biochemistry, Ruđer Bošković Institute, Bijenička cesta 54, HR-10000 Zagreb, Croatia

关键词: alkynes;    azides;    copper;    nucleobases;    N-sulfonylamidine;   

DOI  :  

学科分类：化学（综合）

来源: Croatica Chemica Acta

【 摘 要 】

A series of new aliphatic N-sulfonylamidino thymine derivatives containing nucleobase, N-sulfonyl and amidine pharmacophores in the structure were synthesized by Cu(I)-catalyzed threecomponent coupling of 1-propargyl thymine,...

【 授权许可】

Unknown