Safety Profile and Clinical Recommendations for the Use of Lapatinib

Breast care

Dimitrios Chatsiproios¹ 

[1] aGynäkologisch-onkologische Praxis Kreuzlingen, Switzerland

关键词: Lapatinib;    Tolerability;    Rash;    Diarrhea;    Clinical management;   

DOI  :  10.1159/000285776

学科分类：泌尿医学

来源: S Karger AG

【 摘 要 】

The toxicity profile of agents blocking the epidermal growth factor receptor pathway excludes many of the severe side effects commonly observed with cytotoxic chemotherapy. Like other tyrosine kinase inhibitors, lapatinib is generally well tolerated. Lapatinib exhibits specific toxicities, the most common being diarrhea and rash, which are mostly mild to moderate in severity. Cardiac toxicity is rarely seen with lapatinib. Generally, lapatinib-associated toxicities are manageable.

【 授权许可】

Unknown