Injectable thermoreversible hyaluronan-based hydrogels for nucleus pulposus cell encapsulation

European Spine Journal

Marianna Peroglio¹  Mauro Alini¹  Svenja Illien-Jünger¹  David Eglin¹  Derek Mortisen¹  Christoph Martin Sprecher¹  Sibylle Grad¹ 

[1] AO Research Institute Davos, Clavadelerstrasse 8, 7270 Davos Platz, Switzerland

关键词: Thermoreversible hydrogel;    Hyaluronic acid;    Nucleus pulposus;    Hyaluronan synthase;   

DOI  :  10.1007/s00586-011-1976-2

学科分类：骨科学

来源: Springer

【 摘 要 】

Thermoreversible hydrogels have potential in spine research as they provide easy injectability and mild gelling mechanism (by physical cross-link). The purpose of this study was to assess the potential of thermoreversible hyaluronan-based hydrogels (HA-pNIPAM) (pNIPAM Mn = 10, 20, 35 × 103 g mol−1) as nucleus pulposus cells (NPC) carrier.

【 授权许可】

Unknown