Vascular research using human pluripotent stem cells and humoral factors [Review]

Endocrine Journal

Masakatsu Sone¹  Kazuwa Nakao¹ 

[1] Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto 606-8507, Japan

关键词: Human induced pluripotent stem cell;    Human embryonic stem cell;    Vascular endothelial cell;    Vascular smooth muscle cell;    Vascular hormone;   

DOI  :  10.1507/endocrj.EJ13-0020

学科分类：内分泌与代谢学

来源: Japan Endocrine Society

【 摘 要 】

References(53)Embryonic stem (ES) cells are pluripotent cells collected from the inner cell mass of blastocysts.Induced pluripotent stem cells exhibit characteristics and pluripotency similar to ES cells, even though they were generated from adult somatic cells.We have been investigating the vascular differentiation kinetics of human pluripotent stem cells (PSCs) and their application to human vascular research and clinical medicine.In this review, we present an overview of recent vascular research using human PSCs, focusing on the role of humoral factors and their receptors.We also discuss possible future application of human PSCs to translational research on human vascular disorders.

【 授权许可】

Unknown