Lower physical activity is a risk factor for a clustering of metabolic risk factors in non-obese and obese Japanese subjects: The Takahata study

Endocrine Journal

Takeo Kato¹  Makoto Daimon¹  Kyouko Tada¹  Wataru Kaino¹  Wataru Kameda¹  Isao Kubota³  Kiriko Wada¹  Kaoru Takase¹  Shinji Susa¹  Akira Fukao³  Shigeru Karasawa¹  Takamasa Kayama³  Toshihide Oizumi¹  Satoshi Sasaki² 

[1] The Department of Neurology, Hematology, Metabolism, Endocrinology and Diabetology (DNHMED), Yamagata University Faculty of Medicine, Yamagata 990-9585, Japan;Department of Social and Preventive Epidemiology, School of Public Health, The University of Tokyo, Tokyo 113-0033, Japan;Global Center of Excellence Program Study Group, Yamagata University School of Medicine, Yamagata 990-9585, Japan

关键词: Nutritional intake;    Metabolic syndrome;    Population-based study;    Physical activity;    Obesity;   

DOI  :  10.1507/endocrj.EJ12-0351

学科分类：内分泌与代谢学

来源: Japan Endocrine Society

【 摘 要 】

References(39)Cited-By(2)In several countries including Japan, people without obesity but with a clustering of metabolic risk factors (MetRFs) were not considered to have the metabolic syndrome (MetS).Here, we examined whether lifestyle characteristics differed between non-obese and obese subjects with or without a clustering of MetRFs.From a population-based cross-sectional study of Japanese subjects aged ≥ 40 years, 1,601 subjects (age: 61.9 ± 10.3 years; 710/891 men/women) were recruited.Physical activity status and daily nutritional intake were estimated using questionnaires.A clustering of MetRFs was defined based on the presence of at least two non-essential risk factors for the diagnosis of the MetS in Japan.Energy intake was not higher in subjects with a clustering of MetRFs compared with those without.Among men, energy expenditure at work was significantly lower in non-obese (9.0 ± 8.2 vs. 11.3 ± 9.3 metabolic equivalents (METs), P = 0.025) and obese (9.0 ± 7.9 vs. 11.6 ± 9.4 METs, P = 0.017) subjects with a clustering of MetRFs than in those without.Multiple logistic regression analysis showed that energy expenditure at work was significantly associated with a clustering of MetRFs after adjusting for possible confounding factors including total energy intake.The ORs (per 1 METs) were 0.970 (95% CI, 0.944–0.997; P = 0.032) in non-obese men and 0.962 (0.926– 0.999; P = 0.043) in obese men.Similar associations were not observed in women.In Japanese males, lower physical activity, but not excessive energy intake, is a risk factor for a clustering of MetRFs independent of their obesity status.

【 授权许可】

Unknown