Clinical Efficacy of a Novel Elimination Diet Composed of a Mixture of Amino Acids and Potatoes in Dogs with Non-Seasonal Pruritic Dermatitis

Journal of Veterinary Medical Science

Kenichi MASUDA⁵  Nobutaka YASUDA⁵  Hajime TSUJIMOTO¹  Shinpei KAWARAI³  Keitaro OHMORI⁴  Yasuhiro ASAMI²  Jun ISHIHARA²  Masahiro SAKAGUCHI³ 

[1] Department of Veterinary Internal Medicine, Graduate School of Agricultural and Life Sciences, The University of Tokyo;Nosan Corporation, 46F Yokohama Landmark Tower;First Department of Veterinary Microbiology, School of Veterinary Medicine, Azabu Universit;Laboratory of Veterinary Molecular Pathology and Therapeutics, Division of Animal Life Science, Graduate School, Institute of Symbiotic Science and Technology, Tokyo University of Agriculture and Technology;Animal Allergy Clinical Laboratories

关键词: adverse food reaction;    canine;    elimination diet;   

DOI  :  10.1292/jvms.10-0014

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(36)There has been a need for improvement of the elimination diet used for diagnosis of adverse food reaction (AFR) in dogs. Recently, a novel elimination diet composed of a mixture of amino acids and potatoes was developed. We evaluated the efficacy of the elimination diet for diagnosis of AFR in dogs. Twenty dogs that were suspected to have allergic dermatitis were enrolled in a 2-month food elimination trial using the diet. Before and after the trial, the clinical symptoms were evaluated based on the change in canine atopic dermatitis extent and severity index (CADESI), pruritus score and medication score. Of the 20 dogs, 15 completed the food elimination trial. The remaining 5 dogs were removed from the trial because of diet unpalatability, skin disease progression or diarrhea. On the basis of evaluation of the clinical scores, we observed that the clinical symptoms improved in 11 of the 15 dogs that completed the food elimination trial. Provocative challenge was performed in 10 of the 11 dogs that showed improvement in their clinical symptoms. Of the 10 dogs, 7 were diagnosed as having AFR against food ingredients such as pork, beef, chicken and wheat because their skin symptoms reappeared after intake of these ingredients. The results of the food elimination trial and the provocative challenge indicated the usefulness of the novel elimination diet for diagnosis of AFR.

【 授权许可】

Unknown