Antioxidants in Hypoxic Ischemic Encephalopathy

Journal of Nepal Paediatric Society

PL Prasad¹  AVS Rathee² 

[1] Professor, Department of Paediatrics, Shri Ram MurtiSmarak Institute of Medical Sciences (SRMSIMS),Bareilly, U.P;Resident, Department of Paediatrics, Shri Ram MurtiSmarak Institute of Medical Sciences (SRMSIMS),Bareilly, U.P

关键词: Antioxidants;    birth asphyxia;    hypoxic ischemic encephalopathy;    MDA;   

DOI  :  

学科分类：儿科学

来源: Nepal Paediatric Society

【 摘 要 】

Introduction: Perinatal asphyxia and related injuries are leading cause of morbidity and mortality in India. These babies are at risk to develop hypoxic ischemic encephalopathy (HIE) due to multiple organ including brain damage. The role of malondialdehyde (MDA) as a marker of free radical injury has been well established. Vitamin C and alpha Tocopherols have neutralizing effects on the free radicals. Considering these facts, it was decided to estimate serum MDA level in cases of HIE and the neutralizing effects of Vitamin C and Vitamin E.

【 授权许可】

Unknown