Virulence factors ofEscherichia coli in relation to the importance of vaccination in pigs

Ciência Rural

Oliveira, Luís Guilherme de¹  Nascimento, Karla Alvarenga¹  Vidotto, Marilda Carlos²  Pereira, Daniele Araujo¹  Santos, Anne Caroline Ramos dos¹  Mechler, Marina Lopes³ 

[1] Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP, Jaboticabal, Brazil;Universidade Estadual de Londrina (UEL, Londrina, Brazil;Universidade Federal de Lavras (UFLA, Lavras, Brazil

关键词:  colibacillosis;    diarrhea;    vaccines;    swine;    colostrum;   

DOI  :  10.1590/0103-8478cr20151269

学科分类：农业科学（综合）

来源: Universidade Federal de Santa Maria * Centro de Ciencias Rurais

【 摘 要 】

:Enterotoxigenic Escherichia coli(ETEC) is the major cause of diarrhea in newborn and weaned pigs. Bacteria adhesion to the host cell is considered a specific phenomenon among fimbrial and non-fimbrial adhesins with their respective receptors on enterocytes. Enteric disorders are related with the fimbriae F4 (K88), F5 (K99), F6 (987P), F41, and F18. In addition to ETEC, another category ofE. coli , porcine pathogenicE. coli (PEPEC),can cause diarrhea in pigs; it produces the porcine attaching and effacing-associated (Paa) adhesin in, which is capable to cause a typical lesion known as an attaching and effacing (A/E) lesion. Immunization of sows with adhesin is important to stimulate the production of antibodies and their subsequent transfer to piglets through colostrum. The aim of this paper is to illustrate the main impacts of enteric diseases caused byE. coli in swine production and to highlight the importance of continuing research on this bacterium to improve disease prevention through vaccination.

【 授权许可】

Unknown