Multiple Osseous Metastases of a Carotid Body Tumor in a Dog

Journal of Veterinary Medical Science

Akinori SHIMADA¹  Masako YOSHIKAWA²  Takehito MORITA¹  Koji NISHIDA³  Mina OKAJIMA¹ 

[1] Department of Veterinary Pathology, Tottori University;Alice Veterinary Clinic;Medical Center Nishida Veterinary Clinic

关键词: canine;    carotid body tumor;    osseous metastases;   

DOI  :  10.1292/jvms.69.297

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(7)Cited-By(2)Metastasis of malignant carotid body tumor to multiple bones was detected in a 13-year-old female Siberian husky dog. Radiographs exhibited an abnormal mass in the retropharyngeal site and osteolytic lesions in the vertebral bodies, spinous process, tibia, and ribs. At necropsy, multiple masses were observed in the bones as well as at the dorsal area of the retropharynx. Histologically, the tumor cells, arranged in sheets and clusters, had eosinophilic finely granular cytoplasm. Immunohistochemistry showed the tumor cells were positive for neuron-specific enolase and synaptophysin. Electron microscopy demonstrated a number of dense membrane-bound granules in the cytoplasm of the tumor cells. Based on these findings, this case was diagnosed as multiple bone metastases of a malignant carotid body tumor. Spinal cord damage induced by the tumor mass was the cause of the hind limb paralysis of the present dog.

【 授权许可】

Unknown