Immunohistochemical Survey of the Gut Endocrine Cells in the Common Tree Shrew (Tupaia belangeri)

Journal of Veterinary Medical Science

Eiichi HONDO⁶  Masamichi KUROHMARU¹  Worawut RERKAMNUAYCHOKE⁵  Takao NISHIDA³  Miyuki TAUCHI⁶  Junpei KIMURA²  Nobuo KITAMURA⁶  Hideki ENDO⁴  Yoshihiro HAYASHI¹  Narong CHUNGSAMARNYART⁵  Junzo YAMADA⁶ 

[1] Department of Veterinary Anatomy, Graduate School of Agriculture and Life Science, The University of Tokyo, Tokyo 113-8657, Japan;Department of Veterinary Anatomy, Nihon University, Fujisawa 252-8510, Japan;Laboratory of Anatomy and Physiology, Nihon University, Fujisawa252-8510, Japan;Department of Zoology, National Science Museum, Tokyo 169-0073, Japan;Department of Veterinary Anatomy, Kasetsart University, Bangkok 10900, Thailand;Department of Veterinary Anatomy, Obihiro University of Agriculture and Veterinary Medicine, Obihiro 080-8555, Japan

关键词: immunohistochemistry;    intestine;    stomach;    tree shrew;   

DOI  :  10.1292/jvms.61.761

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(42)Cited-By(10)Regional distribution and relative frequency of endocrine cells in the gastrointestinal tract of the common tree shrew (Tupaia belangeri) were studied immunohistochemically. Ten types of immunoreactive endocrine cells were localized in the gastric mucosa, i.e., chromogranin-, serotonin-, gastrin-, somatostatin-, bovine pancreatic polypeptide (BPP)-, enteroglucagon-, pancreatic glucagon-, peptide tyrosine tyrosine (PYY)-, motilin-, and substance P (SP)-immunoreactive (IR) cells. In the intestine, 13 types of immunoreactive cells were observed, i.e., chromogranin-, serotonin-, somatostatin-, gastrin-, BPP-, enteroglucagon-, PYY-, secretin-, cholecystokinin (CCK)-, gastric inhibitory peptide (GIP)-, motilin-, neurotensin-, and SP-IR cells. The regional distribution and relative frequency of the cell types varied along the gastrointestinal tract. Basically, the types, distribution, and relative frequency of the gut endocrine cells were similar to those reported in other mammalian species. However, some characteristic findings were noted in the present study: (1) the considerably large number of gastrin-IR cells in the pyloric region; (2) numerous serotonin-IR cells in the stomach; (3) appreciable number of BPP-IR cells in the transitional region of the stomach; and (4) wide distribution of PYY- and motilin-IR cells in the gut.

【 授权许可】

Unknown