Leucocytes, fibrinogen and platelets circadian variation in dogs exposed to an inflamatory process and treated with aescin

Ciência Rural

Magalhães, Hilton Machado¹  Fan, Luis Carlos Ribeiro³  Carvalho, Cláudio Baptista de³  Santos, Maria Vargas dos² 

[1] Pontifícia Universidade Calólica do Rio Grande do Sul, Uruguaiana;Universidade Federal de Santa Maria, Santa Maria

关键词: aescin;    circadian variation;    leucocyte;    fibrinogen;    platelet;    inflamatory process;    dogs;   

DOI  :  10.1590/S0103-84781995000100013

学科分类：农业科学（综合）

来源: Universidade Federal de Santa Maria * Centro de Ciencias Rurais

【 摘 要 】

To analyse the circadian variations of the leucocyte, fibrinogen and platelet 20 mongrel male dogs were used divided into two groups of ten animals. The first group was exposed to an inflamatory process induced by the administration of turpentine and after 24 hours the animals were treated with Aesein 1.3mg/kg from 12 to 12 hours. The second group was only exposed to the inflamatory process. Blood samples were performed in all the animals at 0,4am, 8am, 12am, 4pm, 8pm and 12pm hours of the day to examine the parameters. Aescin has determined monocytose at 0,8am, 12am, 4pm and 12pm; linfopenia at 4pm and 12pm; leucocitosis at 0,8pm and 12 pm, as well as an increase in the amount of fibrinogen at 4pm and 12pm; and a decrease in the platelets during all day. Aescin determines unstable circadian variations in the number of leucocyte, platelet and in the amount of fibrinogen in dogs with inflamatory process.

【 授权许可】

CC BY-NC