Inmunomodulatory properties of mesenchymal stem cells

Revista Cubana de Hematología, Inmunología y Hemoterapia

Miranda Rodríguez, Alex²  de León Delgado, Joel²  Galván Cabrera, José A¹ 

[1]Instituto de Hematología e Inmunología, La Habana, Cuba

[2]Centro de Inmunología Molecular, La Habana, Cuba

关键词: mesenchymal stem cells;    immunomodulation;    therapeutic effects;   

DOI  :  

学科分类：生理学与病理学

来源: SciELO

【 摘 要 】

Cellular therapy is a versatile therapeutic approach that has been assessed on tissue regeneration, on the enhancement of tumor specific immune response, on the delivery of drugs to damage tissues and on the restoring of tissue homeostasis at chronic inflamed sites. Among the cell populations used for cellular therapy, multipotent mesenchymal stem cells (MSC) appear as a heterogeneous group of cells with the highest potentiality based on its low immunogenicity and its ability to exert a plethora of immunomodulatory effects. This paper reviews the experimental evidences accumulated during the last decade in order to estimate the relevance of MSC for therapies based on cellular transference.

【 授权许可】

CC BY-NC