Molecular Epidemiology of Paramyxoviruses in FrugivorousEidolon helvum Bats in Zambia

Journal of Veterinary Medical Science

Takashi KIMURA¹  Akihiro ISHII⁴  Emiko NAKAGAWA⁴  Aaron MWEENE²  Yuka THOMAS⁴  Hirohito OGAWA⁴  Bernard HANG’OMBE³  Boniface NAMANGALA³  Walter MULEYA¹  Ayato TAKADA⁵  Michihito SASAKI¹  Hirofumi SAWA¹  Yasuko ORBA¹ 

[1] Division of Molecular Pathobiology, Research Center for Zoonosis Control, Hokkaido University, N20, W10, Kita-ku, Sapporo 001�?0020, Japan;Department of Disease Control, School of Veterinary Medicine, University of Zambia, Lusaka, Zambia;Department of Paraclinical Studies, School of Veterinary Medicine, University of Zambia, Lusaka, Zambia;Hokudai Center for Zoonosis Control in Zambia, Research Center for Zoonosis Control, Hokkaido University, N20, W10, Kita-ku, Sapporo 001�?0020, Japan;Division of Global Epidemiology, Research Center for Zoonosis Control, Hokkaido University, N20, W10, Kita-ku, Sapporo 001�?0020, Japan

关键词: bat viruses;    epidemiology;    paramyxoviruses;    virus;    Zambia;   

DOI  :  10.1292/jvms.13-0518

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(19)Cited-By(3)In this study, we describe the detection of novel paramyxoviruses from theEidolon helvum species of fruit bats. We extracted RNA from 312 spleensamples from bats captured in Zambia over a period of 4 years (2008�?2011). Semi-nestedRT-PCR detected a total of 25 (8%) positive samples for paramyxoviruses which were thendirectly sequenced and analyzed using phylogenetic analysis. Among the positive samples,seven novel paramyxoviruses were detected. Five viruses were closely related to the genusHenipavirus, while two viruses were related to the unclassified Batparamyxoviruses from Ghana and Congo Brazzaville. Our study identified novelHenipavirus-related and unrelated viruses using RT-PCR in fruit bats from Kansaka NationalPark and indicated the presence of similar Bat paramyxoviruses originating from widegeographic areas, suggesting the ability of bats to harbor and transmit viruses. Thepresence of these viruses in fruit bats might pose a public health risk.

【 授权许可】

Unknown