Utility of a guided reading technique for cervical cancer screening.

Colombia Médica

María Eugenia Niño³  Luis Alfonso Díaz¹  Hernando Pardo² 

[1] Universidad Autónoma de Bucaramanga, Bucaramanga;Liga Santandereana de Lucha contra el Cáncer;Universidad Autónoma de Bucaramanga, Bucaramanga

关键词: Cervical cancer;    Cervicovaginal cytology;    Screening;   

DOI  :  

学科分类：医学（综合）

来源: Universidad del Valle * Facultad de Salud / Universidad del Valle, Faculty of Health

【 摘 要 】

Background:Reading of Papanicolaou test slides follows a pattern that could omit sectors with abnormal cell nests. A low-cost guided reading strategy has been designed.Aim:To establish criteria validity and reproducibility of guided reading strategy in cervical uterine Pap smear.Methodology:To each of 300 women without cervical cancer history in order to apply Papanicolaou test, two slides were taken; both slides were read by regular method, and then reevaluated in blinded conditions with a guided technique. Diagnosis accuracy of regular and guided techniques was determined using pathologist’s reading as a gold standard.Results:When regular readings were used 65 (21.7%) of women had abnormal cytology, and 64 (21.3%) had also abnormal readings with the guided technique. Concordance of the regular reading (Kappa 0.354; 95% CI 0.250-0.457) improved with the guided technique (Kappa 0.395; 95% CI 0.285-0.505), while 24.3% slides were found abnormal in gold standard (2.7% with a high degree of malignancy). The guided reading improves all criteria validity indicators.Conclusion:This study demonstrated that the guided reading improves criteria validity indicators, correcting some technician mistakes; however, a populational study is necessary to confirm these results.

【 授权许可】

Unknown